Automated Non-contact Liquid Volume Detection for 384 Format Well Plates
The VolumeCheck 384 uses ultrasonic technology to measure the height of the sample meniscus without coming into contact with the sample. The volume of each well of a 384 well plate is returned in 30 seconds in Fast Scan Mode and in 2-3 minutes in Standard Mode. This easy to use system provides a robust alternative to manual or visual well plate inspection.
All designed, fabricated, and tested in our Concord, CA facility made from the highest quality materials.
Automation Benefits
- Replaces visual or manual inspection of well plates
- Outputs sample volume for each well or tube
- Detects and reports empty wells
- Provides QC step for assay plate creation
- Verifies sample volume before and after liquid handling operations
- Compatible with wide variety of common ANSI/SLAS standard racks and plates
- No consumables needed — works with your racks and plates
- No rack adapters needed
Applications
- Low or high sample volume detection in uncapped consumables
- Sample library inventory management
- Assay plate quality control
- QC/QA for assay development and DNA processing
- Detect sample volume for incoming plate samples
- Vlume verification for plates before and after liquid handling
The VolumeCheck is Utilized Worldwide by
- Genomic Biobanks
- Drug Discovery Laboratories
- Molecular Biology Laboratories
VolumeCheck™ Software
- Graphically displays well-by-well volumes in an on-screen color map
- Outputs volume data in customizable CSV file for Excel or LIMS
- Integrates with LIMS and other robotics using ActiveX Toolkit
- Windows based (10, 8, 7, Vista)
Compatible Labware
- PCR plates / assay plates
- Shallow / deep well plates
- 384, 96, 48, & 24 ANSI/SLAS standard well labware
- Vials or tubes up to 92mm in height
- Uncapped or unsealed labware
- Wide variety of common ANSI/SLAS standard racks and plates
- No consumables needed — works with your racks and plates
- No rack adapters needed

Key Features
Outputs Sample Volume For Each Well
Collects and outputs sample volume data for each well position
Works With Common Lab Solutions
Compatible with Water / Alcohol / DMSO and more based samples
Fast Rack/Wellplate Scanning
Scans a 384 well plate in 30 seconds in Fast Scan Mode! and 2-3 minutes in Standard Mode
Scans a 96 well plate in one minute
System Resolution and Accuracy
The VolumeCheck 384 liquid level sensor is capable of sensing changes in sample volume in the sub 2-3 μL range.
We Support You with Every Step
An in-house BioMicroLab technician will unpack and install the instrument in your lab… and then train your team to get you up and running. We also offer online training sessions at anytime.
How It Works
The VolumeCheck uses ultrasonic technology to measure the distance between the sensor and the height of the meniscus. It then extrapolates the distance from a calibration table created by the user and outputs the volume. The technology allows for sample measurement of sample volume in a wide variety lab ware.

The VolumeCheck software calibration wizard assists the user in efficiently creating the calibration table, which is based on known volumes of a given sample. Many calibration tables can be stored, making it easy to switch between sample types and different types of labware.
The resolution and accuracy will depend on whether the samples were centrifuged, any dimensional variation in labware consumables, the accuracy of the calibration tables created by the user, and the sample volume in the plates. The VolumeCheck returns a higher resolution with low volume plates vs. higher volume plates (PCR plates vs. 2.2mL deep well plates).
The VolumeCheck exhibits good repeatability, which makes it an appropriate choice for many volume inspection tasks.
VolumeCheck Quote Wizard
VolumeCheck™ Software
- Generates an output file (.csv) of volume data on a well-by-well basis
- Graphically displays the well plate volumes in columns and rows
- User interface designed for quality control applications
- Project-based software for multiple types of applications and labware
- Select rows or columns to scan for efficient throughput
- Includes plate data calibration table utility
- Easy-to-use Windows based software
- ActiveX toolkit available for integration projects
- Prints or generates a PDF of plate reports
The VolumeCheck software calibration wizard assists the user in efficiently creating the reference curve, which is known volume vs. distance measure to the meniscus for a given sample. Many reference curves can be stored, making it easy to switch between sample types and different types of labware.
The VolumeCheck is compatible with a wide variety of common labware. System resolution can be optimized when plates are centrifuged, any dimensional variation in consumable is minimized, and reference curves most closely represent sample type scanned. The VolumeCheck returns a higher resolution with low volume plates vs. higher volume plates (PCR plates vs. 2.2mL deep well plates).
OEM Compatibility
BioMicroLab Integrates with Other Automation Equipment! BioMicroLab offers both ActiveX and SDK Toolkits for all our instruments for end-users, integrators, and other manufacturers to fully integrate a BioMicroLab instrument with other robotics and LIMS systems.
VolumeCheck
-
- Beckman Coulter
- Green Button Go™ by Biosero
- Tecan
- Titian – Mosaic Sample Management Software – Learn more on Titian’s website
Please inquire about OEM Capabilities!
We are happy to share the documentation associated with the ActiveX toolkits for your review. Please email us to request copies of the manuals. VolumeCheck ActiveX and SDK Toolkits are an optional purchase.
Fact Sheet

Compatible With All Popular Labware

Specifications
Ordering Information
VolumeCheck 384
Part Number: BML-VC-384
Throughput
The VolumeCheck 384 liquid level sensor is capable of sensing changes in sample volume in the sub 2-3 μL range.
The VolumeCheck 384 system resolution can be maximized by:
- Centrifuging sample plates to provide a consistent sample level
- Ensuring the calibration table is optimized to the consumables and type of sample
- Reducing dimensional variation in labware
Dimensions
11”W x 26.5”D x 12.5”H (28 cm x 68 cm x 32 cm)
Weight
33.25 lbs. (15 kg)
System Requirements
Operating System: Windows 10, 8, 7; ~2GB RAM Recommended
One USB Port
Ask us about our laptops, preconfigured with BioMicroLab software!
Electrical
110-220 VAC ~ 50/60Hz
IQ/OQ
Installation Qualification / Operational Qualification Available
Features
- Outputs sample volume for each well
- Compatible with Water / Alcohol / DMSO and more based samples
- Simple reference curve creation utility included
- Fast scan speed
- Typical accuracy of sub 2-3 μL range with a 1.4mL well
- Compatible with labware up to 92 mm in height
- Small footprint: 11”W x 26.5”D x 12.5”H (28 cm x 68 cm x 32 cm)
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detailed information about this product.
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Company Info
BioMicroLab, Inc. | A division of CopyPro, Inc.
2500-A Dean Lesher Dr. | Concord, CA 94520 USA
Jobs
BioMicroLab offers career opportunities for talented and motivated individuals in positions across the company at our facility in the San Francisco Bay Area.
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