XL20 Tube Handler™

Automates tube re-arraying, sample weighing, volume tracking, & labeling for 96 tube rack samples.

XL20 is a simple-to-use automated pick and place tube handler for 96 tube rack samples. The XL20 automates sample tube sorting, 2D sample tracking, and sample weighing tasks. The XL20’s workflow oriented software controls the automatic transfer of sample tubes to 2D barcode reader, tube balance, and volume measurement options. The XL20 software logs all collected data (sample 2D code, sample weight, etc.) to output files. A proven sample management tool, the XL20 works well as primary automation platform for labs with growing sample libraries, and as complementary automation for larger core facilities.

All designed, fabricated, and tested in our Concord, CA facility made from the highest quality materials.

Automation Benefits

Since 2004, XL20 Tube Handlers have been automating workflows in laboratories around the world! It is an ideal benchtop robot for use alongside fully automated sample stores!

  • 18 – 20 rack deck provides hours of “walk-away” time
  • Modular by design–your instrument will include just the capabilities you require for your workflow
  • Fully compatible with LIMS systems
  • Easy-to-use Software
  • Automates handling of 0.3 mL to 1.4 mL microtubes
  • Compound sample library management
  • Re-array and cherry pick samples prior to liquid handling
  • QA/QC
  • Save freezer space by consolidating tube rack samples
  • Print and apply human readable and barcode labels
  • Track sample volume data across compound library
  • Collect DMSO hydration with TubeDowser
Typically Installed In
  • Compound Libraries / HTS groups
  • Biobank / Biorepositories
  • Core Genomic Facilities
  • Molecular Diagnostic Testing Labs
XL20 Tube Handler

Key Features


Scan. Decode. Detect Volume. Re-array. Label.

Built with the features you need for your workflow, the XL20 can be used for a single operation, or to accomplish multiple tasks such as scanning, weighing and labeling!


Small Footprint

While only requiring about 29″ x 21″ (72 x 53 cm) of bench top space, the XL20 is ideal for laboratories with limited space.


Proven Reliable and Flexible

For managing 2D barcoded 96 well tubes, there is no tube handler more reliable, flexible, or affordable than the XL20! Supported by an experienced team since its debut in 2004, the XL20 continues to be a workhorse in laboratories across the industry!


We Support You with Every Step

An in-house BioMicroLab technician will unpack and install the instrument in your lab and train your team to get you up and running. We also offer online training sessions at anytime.


XL9 / XL20 Configuration Overview

Each instrument is configured with the Modules and Add-On Features your laboratory needs. The main difference between the two instruments is the rack capacity.


Modular by Design



Re-array, Reformat, Cherry Pick

This core feature, included with all models, is central to all tube handling operations. For labs with small or large sample libraries, the XL20 sorts up to 700 tubes per hour, providing unattended tube processing for work list based tube transfer from source racks to target racks.


Sample Identification & Tracking

The XL20 seamlessly integrates 2D data matrix barcode decoding with all other tube handling operations, decoding up to 500 tubes per hour. BioMicroLab’s software captures and reports the tube’s 2D barcode, tube location, weight, volume and more to LIMS systems!


Label Printing & Application

Labeling tubes by hand is labor intensive. Let the all electric LabelPro do it for you! The labeling module attaches to the front of the XL20 (requiring 2 deck positions) and prints and applies high-resolution 1D & 2D barcodes as well as human readable text and symbols! User-friendly software allows operators to generate unique or identical labels using a variety of label materials and sizes.


Volume Detection

To verify volume upon receipt of samples, or before/after liquid transfer operations, the XL20 integrates either a precision automated balance or the non-contact sensor based LevelCheck™ to automate the collection of sample weight data.

Cold Room Compatibility

The XL Series accommodates lab requirements for maintaining sample temperature in cold storage, refrigeration systems and cold rooms. Cold room compatible XL20 units used for re-arraying tubes are capable of operation to -10°C. Units equipped with an automated balance are capable of operation to -4°C. Given the compact size, the XL20 fits nicely in freezers and cold rooms where space is often limited. Cold room compatible XL Series units operate in the exact same way as they would in in ambient environment.


When operator safety is a concern, your XL20 can be enclosed so that the instrument automatically shuts off when the door is opened. Clear, acrylic walls allow maximum light and visibility into the instrument for operator ease-of-use.

XL Quote Wizard


User-friendly Windows based software is included with all XL Series instruments to manage sample processing modes and robotic operations. BioMicroLab offers software developer toolkits for your instrument and workflow integration projects.

XL Work List Manager Software

Included with all XL Series instruments, the XL Work List Manager Software provides control of all vial pick and place operations. It provides multiple tube processing modes for common tube handling applications to meet your varied workflow needs and allows you the flexible control you need to increase your throughput. Output files can be configured to meet your LIMS system requirements. Easily managed by multiple users, our full featured tube processing software provides unattended operation to meet your group’s throughput requirements.

Advanced system error handling options provide unattended operation. Output files can be configured to meet your LIMS system requirements.


  • User-friendly point-and-click Graphical User Interface
  • Data collection and worklist based processing modes
  • Guides the user through the tube rack loading and unloading process
  • Interactive interface provides feedback while processing tubes
  • Dynamically processes work lists with more racks than the XL Series platform capacity
  • Integrates with hand-held barcode scanners for rack identification
  • LIMS integration ready output files in .csv file format
  • Tracks and logs all system activity
  • Provides robust error-handling options for unattended tube processing
  • SDK & ActiveX toolkits available

Compatible Labware

The XL20 is compatible with 96 well ANSI/SLAS microtubes (0.3 mL to 1.4 ml) from major labware manufacturers. Please inquire if you do not see your labware listed, as it still may be compatible!

  • 96 format ANSI/SLAS tube racks
Compatible Manufacturers
  • Altemis
  • Biosero
  • FluidX
  • Greiner
    • Micronic
    • Thermo Scientific (Matrix, ABgene)
    • Ziath

and more!


Operational Mode Tubes / Hour
Re-array only 700
Re-array and 2D Decode 500
Re-array, 2D Decode and Weigh ~250
Re-array and Weigh ~300
Re-array, 2D Decode & LevelCheck 350-400
Re-array, 2D Decode & DMSO Check 350-400
Re-array and Label 180

XL20:  28.5” W x 21” D x 16” H (72 x 53 x 40 cm)
XL20 with Labeling:  28.5” W x 31” D x 16” H (72 x 79 x 40 cm)


XL20  ~60 lbs (27.2 kg)
XL20 with Labeling: ~82.5 lbs (37.4 kg)

Actual weight depends on the configuration options

System Requirements

Operating System:  Windows 10, 8, 7; ~2GB RAM Recommended
USB Ports:  Two

Ask us about our laptops, preconfigured with BioMicroLab software!


100-240VAC ~ 50/60Hz

Operating Environment

XL20: 10°C to 40°C, 10-90% RH
XL20 for Cold Rooms: -4°C to 40°C, 10-90% RH


  • Automates collection of tube 2D barcode, weight, volume, and DMSO hydration
  • Decodes 2D barcode with integrated camera
  • Weighs sample with 0.1mg 4-place balance (with Automated Balance option)
  • Scans sample volume in capped tubes (with LevelCheck option)
  • Scans sample DMSO hydration (with TubeDowser option)
  • Print and apply labels (with labeling option)
  • Enclosure available for operator safety!
  • Small 18” x 21” footprint
  • Compatible with 96-well ANSI/SLAS standard tube racks
  • Includes LIMS compatible BioMicroLab XL Series Work List Software

Fact Sheet

Download a printable PDF with
detailed information about this product.

More Resources


Fact Sheet

Download a printable PDF with detailed information about this product.

Product Presentation

Download a detailed Product Overview as a printable PDF.


Evaluation Unit

Want to try before you buy? Request an evaluation unit for this product.

Have a Team Member Contact Me

Have one of our knowledgeable representatives contact you.

Company Info

+1 (925) 689-1200 | sales@biomicrolab.com
BioMicroLab, Inc. | A division of CopyPro, Inc.
2500-A Dean Lesher Dr. | Concord, CA 94520 USA

BioMicroLab offers career opportunities for talented and motivated individuals in positions across the company at our facility in the San Francisco Bay Area.

Schedule a Demo

We know how important it is to find the right instrument for your lab! During our convenient online demos, you'll see the instrument in action.

Get Support

Need help with one our products? Send us an email at biomicrolabsupport@sptlabtech.com and we'll respond the same day.

Send A Message

©2021 BioMicroLab, Inc. | All rights reserved